I am a theoretical physicist. My scientific activities concern Statistical Mechanics of Complex Systems in Physics and applications to Molecular Biology, with mathematical and computer approaches. I worked at ESPCI in Paris, Imperial College London, and at the UK Complexity Science Centre in Warwick. My group is now based at the Physics Department of the University of Naples "Federico II". In 2016 I was the recipient of the Einstein BIH Award by the Einstein Foundation and I am Visiting Professor at MDC in Berlin. I am the national coordinator of IS-BioPhys, the INFN project on the applications of the methods of Theoretical Physics in Biology, and I am a member of The 4D Nucleome consortium of the NIH in the US and of the Berlin Institute of Health in DE. I serve in international panels for the management of research and its resources, including the ANR in France, and in the EPJP and FPB boards.
We investigate the molecular mechanisms underlying genome regulation in eukaryotes, by combining their Statistical Physics description, computer simulations, and high-throughput data analysis. In particular, we work on chromosome 3D organization (see a recent NATURE and a recent NATURE SMB) and single-cell transcription data analysis (see a recent GENOME BIO.). We have also discussed the symmetry-breaking events leading to X Chromosome Inactivation (see a NATURE PHYS. N&V).
In Physics, we have been working on equilibrium and off-equilibrium critical phenomena, disordered and glassy systems, vortices in superconductors and, in particular, on granular media (see a review in NATURE MAT.).
Prof. Mario Nicodemi,
Dipartimento di Fisica "E. Pancini",
Universita' di Napoli "Federico II",
Complesso Universitario di Monte S. Angelo,
Via Cintia, 80126 Napoli, ITALY
TEL: +39 081 676475
EMAIL: Mario.Nicodemi "-at-" na.infn.it