Physics Department, Uni.NA

Theoretical Physics & Statistical Mechanics

Mario Nicodemi


I am Full Professor at the Physics Department of the University of Naples "Federico II" and Einstein BIH Visiting Professor at the MDC in Berlin. My scientific activities concern Statistical Mechanics of Complex Systems in Physics and applications to Molecular Biology, with math, physics and computer approaches. I worked at ESPCI in Paris, Imperial College London, and at the UK Complexity Science Centre in Warwick. I coordinate the INFN Biological Physics national project (IS) in IT, and I am a member of the NIH 4D Nucleome consortium in the US and of the Berlin Institute of Health in DE. I also serve in international panels for the management of research and its resources, including the ANR in France and in the EPJP board. In 2016 I was the recipient of the Einstein BIH Fellowship award from the Einstein Foundation in Berlin.

Research Interest Summary

Enzo Mari's puzzle

My group works on the Physics of Complex Systems and its applications to Molecular Biology, combining physics models, computer simulations, high-throughput data analysis and the development of new technologies. In particular, we contributed to the investigation of the off-equilibrium dynamics of granular media and glassy materials, and to the understanding of the three-dimensional architecture of the mammalian genome and its links with gene regulation. Here is a selected list of my publications and more details on my current research projects.

Statistical Physics, Computational and Systems Biology: we investigate the molecular mechanisms underlying genome regulation in eukaryotes. In particular, we work on chromosome 3D organization (see a recent NATURE, a NATURE GEN. and NATURE SMB) and single-cell transcriptional activities (see a recent GENOME BIO.). We have also discussed the symmetry-breaking events leading to X Chromosome Inactivation (see a NATURE PHYS. N&V).

Statistical Mechanics of Complex Systems: in Physics, we have been working on equilibrium and off-equilibrium processes, phase transitions and critical phenomena, in disordered and glassy systems, vortices in superconductors and, in particular, on granular media (see a review in NATURE MAT.).

Research Group

Research group 01/2016

Current members:
Simona Bianco, Andrea Chiariello, Mattia Conte, Andrea Esposito (at MDC/UniNA), Luca Fiorillo, Francesco Flora, Ehsan Irani (at MDC), Francesco Musella, Mario Nicodemi

Renato Sciarretta, Alfonso Corrado, Carlo Annunziatella, Raffaele Campanile, Andrea Piccolo, Mariano Barbieri, Sergio Sarnataro, Giovanni Terzo, Giovanni Laudanno, Pasquale Franzese, Anna Longobardi, Anas Rana (at UoW with S. Mukherjee), Emanuela de Falco, Ciro di Lanno, Gaetano Pellegrino (at Uni.Na with A. Corazza), Jon Armond (at UoW with S. Mukherjee), Denis Grebenkov, Dan Barker (at UoW with S. Mukherjee), Melania Barile, Paolo Casale, Polly Downton (at UoW with G. Koentges), Antonio Scialdone, Valentino Bianco, Sam Brand (at UoW), Ilaria Cataudella, Deborah Pallotti



Openings are available for PhD and Post Doctoral positions in our group, for up to 3 years. Interviews are in March and September 2020.

The research topics concern the molecular mechanisms underlying the 3D organisation and regulation of the genome in eukaryotes, by combining polymer physics, computer simulations and experimental high-throughput data analysis. The ideal candidate should have a background in statistical mechanics or computer simulations, biological physics, bioinformatics. She/He will work within a collaboration including physicists, molecular biologists, and bioinformaticians across EU and USA. Additional information is available at the group research page or via email requests. In our group the successful candidate will find very friendly and open working conditions, dedicated supervision and many learning and interaction opportunities.

Informal enquiries and applications (including a cover letter, CV with publications and names of three potential referees, in a single pdf) should be sent by email.

Contact us

Prof. Mario Nicodemi,
Dipartimento di Fisica "E. Pancini",
Universita' di Napoli "Federico II",
Complesso Universitario di Monte S. Angelo,
Via Cintia, 80126 Napoli, ITALY

ROOM: 2Ma14

TEL: +39 081 676475

EMAIL: Mario.Nicodemi "-at-"